ELAVL1 and inflammatory bowel disease: That HuR enhances ATG16 mRNA translation was also demonstrated in intestinal epithelium cells in vitro and in vivo in a mice line with intestinal epithelium-specific ablation of HuR (IE-HuR−/−); human intestinal mucosa from patients with Inflammatory Bowel Disease exhibit decreased levels of both HuR and ATG16L1, this is an interesting finding since autophagy is frequently defective in those patients (53).