Importantly, ITGA2 was correlated with the prognosis of GC patients who received 5-fluorouracil (5-FU) treatment, and an increased level of ITGA2 was correlated with decreased overall survival, first progression and post-progression survival times according to the Kaplan-Meier Plotter database (34) (Figure 1E). Here, ITGA2 is linked to gastric cancer.