The miR-302/367 cluster was recently shown by Guo et al. to be elevated in prostate cancer compared to normal prostate tissue, and shown to promote proliferation and androgen-independence by targeting the tumor suppressor gene LATS2 (46), suggesting that the role of these microRNAs may be a cumulative effect of several functional phenotypes. The gene discussed is LATS2; the disease is prostate carcinoma.