For example, we find that for low-grade PCa, both AICEs and GRSs of AAs are statistically significantly higher than those of EAs over most of the studied genomic aberrations (i.e., ERG fusions, somatic mutations in SPOP, BRCA2, and FOXA1, germline mutations in BRCA2 and BRCA1, and CNAs in ERG and FOXA1). This evidence concerns the gene SPOP and posterior cortical atrophy.