NES and brain neoplasm: We have previously demonstrated that in the neurogenic niches, Btg1 controls the quiescence and self-renewal of the stem cells (11, 29), then by qRT-PCR, we also evaluated in the MBs the mRNA levels of some markers of brain tumor stem cells, such as nestin, glial fibrillary acidic protein (GFAP), CD133, and CD15 (38, 61–68).