We have previously demonstrated that in the neurogenic niches, Btg1 controls the quiescence and self-renewal of the stem cells (11, 29), then by qRT-PCR, we also evaluated in the MBs the mRNA levels of some markers of brain tumor stem cells, such as nestin, glial fibrillary acidic protein (GFAP), CD133, and CD15 (38, 61–68). The gene discussed is PROM1; the disease is brain neoplasm.