PLK1 was widely over expressed in a broad spectrum of human cancers, such as breast cancer 15, colorectal cancer 16, glioma 17, non-small cell lung cancer 18 et al. Also, the elevated expression of PLK1 has prognostic value for predicting poor outcomes in patients in a variety of cancers 19-21. The gene discussed is PLK1; the disease is non-small cell lung carcinoma.