MAPK1 and ovarian carcinoma: To confirm the hypothesis that DUSP6 increases the proportion of cells in G0/G1 phase of the cell cycle in ovarian cancer cells by negatively regulating the ERK signaling pathway, which leads to cellular quiescence and therefore causing chemotherapy- resistance, we use FACS to conduct a cell cycle analysis in DUSP6 overexpressing and control SKOV3 cells.