P2RY2 and synovial sarcoma: These diverse P2Y2R signaling pathways have been implicated in a number of pathologies, including Alzheimer’s disease (Ajit et al., 2014), cardiovascular disease (Chen et al., 2017), cancer (Hu et al., 2019), SS (Woods et al., 2018), and hantavirus cardiopulmonary syndrome (Bondu et al., 2018), as well as processes such as wound healing (Jin et al., 2014) and tissue regeneration (El-Sayed et al., 2014).