IL1B and synovial sarcoma: P2X7R antagonism also significantly reduced salivary gland expression of immunoactive molecules known to be upregulated in salivary gland biopsies isolated from SS patients, including IL-1β, ICAM, VCAM, E-selectin, CD80, and CD86 (Tsunawaki et al., 2002; Khalafalla M.G. et al., 2017).