The incidence of breast cancer in young women (aged <40) is low, but increasing.11 Young women are more likely to have breast cancer with adverse biological features, including higher grade, absence of hormone receptors, lymph node involvement and vascular invasion.12 Young age has been consistently shown to be an adverse prognostic factor, with a higher risk of distant recurrence.11 In addition, this group is less likely to have co-morbidities; they may tolerate chemotherapy and other treatments better than older patients. The gene discussed is NR4A1; the disease is breast cancer.