To elucidate the effect of SNP rs17079281 on expression of gene DCBLD1, we analyzed the relationship between DCBLD1 genotype and phenotype in lung tumor samples, and found an expression quantitative trait loci between SNP rs17079281 and DCBLD1 mRNA levels in lung adenocarcinoma tissues, but not in lung squamous cell carcinoma. This evidence concerns the gene DCBLD1 and squamous cell lung carcinoma.