PCDHGA9 and gastric cancer: Interestingly, upon exploring the subcellular localization of β-catenin by western blotting and confocal microscopy, we observed increased membrane β-catenin levels and decreased nuclear β-catenin levels in PCDHGA9-overexpressing GC cells, whereas PCDHGA9-silenced cells showed the opposite phenomenon, which may indicate that PCDHGA9 affects β-catenin distribution and strengthens the stability of membrane-bound β-catenin.