Our results demonstrated that vaccination with pcHrp1 or pcHrp1+pcIL-34 could significantly trigger the expression of IL-8, CCL2, CXCL9, CXCL10, and CCL20, indicating that the chemokines were involved in the recruitment of neutrophils, monocytes, Th1 cells, and Th17 cells to the infection sites. The gene discussed is CCL2; the disease is infection.