GSK3B and peritonitis: In mice with peptidoglycan (PGN)-induced peritonitis, anti-inflammatory effects (increased IL-10, decreased TNF, IL-1β, IL-6) could be elicited by ephedrine hydrochloride (EH), a substance that inhibits GSK3β via the PI3K-Akt axis in cell culture experiments [148] (see Section 3.1.3).