Additionally, a significant difference in NT-proBNP was found between patients in the brain hemorrhage and control groups (WMD = 586.44, 95% CI = 474.07–698.81, p <0.00001, I2 = 73%, p-value of heterogeneity = 0.02) (Figure 4). The gene discussed is NPPB; the disease is intracranial hemorrhage.