BCL2 and colorectal carcinoma: Huang and colleagues performed a meta-analysis on 40 CRC articles involving 7,658 patients and found high Bcl-2 expression correlated with favorable OS (pooled HR, 0.69; 95% CI, 0.55–0.87; p = 0.002) and better DFS/RFS (pooled HR, 0.65; 95% CI, 0.50–0.85; p = 0.001).