While the RPPA platform did not have antibodies recognizing phospho-Lck, Fyn or phospho-Fyn, the antibodies for Src and phospho-Src (Tyr527, Tyr416) provided surrogates for evaluating the effects of Dasatinib on T cells as well as PCa cells and Gr-MDSCs. Here, LCK is linked to posterior cortical atrophy.