Rather, the colonic CD14+CD163− MNPs display Mo-like morphology, share gene expression with monocytes (FCAR/CD89 and C5AR1/CD88), and are molecularly and functionally distinct from the CD14brightCD163+ Mɸ subset detected in inflamed IBD mucosa [31], RA synovial fluid, and tumor ascites [51]. This evidence concerns the gene C5AR1 and neoplasm.