CLEC10A and melanoma: Brown et al. identified two murine cDC2 subsets in spleen: pro-inflammatory RORγt+CLEC10A+CLEC12A+ “cDC2B” resembling circulating DC2 in healthy subjects as well as colonic CD14 negative CD1c/ CLEC10A cluster in CD patients [31], and anti-inflammatory Tbet+ “cDC2A”, with the human counterpart detected in spleen and melanoma [53].