For instance, ectopic transfections of miR-34c were reported to inhibit the growth of gastric cancer cells through suppression of the expression of cyclin-dependent kinase 4 (CDK4) and cyclin E2 (CCNE2) even if no direct interaction was demonstrated between the miRNA and these mRNAs (Figure 9) [37]. Here, CCNE2 is linked to gastric cancer.