Against the background of lung cancer, metabolic changes were observed, characterized by a decrease in the de Ritis coefficient due to an increase in the activity of alanine aminotransferase against the background of an increase in the activity of gamma-glutamyltransferase and alkaline phosphatase, as well as a decrease in the activity of lactate dehydrogenase (Table 2) [83]. This evidence concerns the gene GPT and lung carcinoma.