The observation of higher serum levels of PTH and 1,25(OH)2D in untreated CeD also implied the possibility that the stimulatory effects of PTH and 1,25(OH)2D on kidney tubule Ca reabsorption were the true determinants of the relative hypocalciuria classically reported in CeD [32,33]. Here, PTH is linked to cranioectodermal dysplasia.