The proportion of CD11b+Gr-1+(high) neutrophils in the BALF and lung cells of CFD-induced COPD murine model was higher than that in the untreated group, whereas the proportion of CD11b+Gr-1+(high) neutrophils in GG, AR, GG plus AR, GA, and TN-treated mice was lower than that in the CFD-induced control mice (Figure 6A–D). Here, ITGAM is linked to chronic obstructive pulmonary disease.