GH1 and atherosclerosis: Much evidence supports the participation of local or circulating GH in vascular homeostasis, because when a deficiency of this hormone is present, an endothelial dysfunction appears with serious consequences; this is most likely the reason by which untreated GH-deficiency (GHD) is associated with an increased risk of atherosclerosis and vascular mortality, while GH treatment may reverse early atherosclerosis [2,3,4,5].