FGF2 and non-small cell lung carcinoma: To facilitate the intracellular delivery of FGF-2 and determine its effects on NSCLC cell proliferation, survival, and intracrine signaling, we synthesized a neutralized alginate-graft-poly(ethylene glycol) (Alg-g-PEG) copolymer and ionically crosslinked it to form Alg-g-PEG-based nanoparticles (ABNs).