WT cells showed a clear upregulation of main stemness markers, together with the newly reported induction of CDH5 and the protease ADAMTS1. While CDH5 has been already related with stemness parameters [17,33,34] as a causal factor of vasculogenic mimicry events, our data exposed that extracellular proteases such as ADAMTS1 should also been considered when studying the stemness capacities or the aggressiveness of a tumor. This evidence concerns the gene ADAMTS1 and neoplasm.