CXCL8 and neoplasm: However, the tumor adhesion ability enhanced by DKO-1-Exos was significantly reduced after treatment with DNAse which inhibited the formation of NETs, and DKs-8 tumor adhesion induced in the presence of DKO-1-Exos was significantly increased after the addition of IL-8, but decreased after addition of anti-IL-8 (Fig. 6a, p < 0.05).