Moreover, some new insights on the role of PVT1 in drug response are emerging, including the elevated expression of both PVT1 and circPVT1 in the vincristine-resistant AMU-ML2 DLBCL line [64] and the glucocorticoid-resistant phenotype promoted by circPVT1 in MM models, that is rescued by knockdown [70]. This evidence concerns the gene PVT1 and diffuse large B-cell lymphoma.