Axonal Guidance Signaling, LXR/RXR Activation, LPS/IL-1 Mediated Inhibition of RXR Function, Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis, Hepatic Fibrosis / Hepatic Stellate Cell Activation, FXR/RXR Activation, were selected as the top pathways enriched using the significant mRNAs. The gene discussed is NR1H4; the disease is Hepatic fibrosis.