TMEM18 and Obesity: Taken together, among seven common obesity risk loci, the loci near TMEM18 (rs6548238), CDKAL1 (rs7754840), and FAIM2 (rs7138803) are associated with obesity, and loci near TMEM18 (rs6548238) and FAIM2 (rs7138803) are susceptibility loci for obese type 2 diabetes.