SH2B1 and type 2 diabetes mellitus: However, the loci near GNPDA2 (rs10938397), SH2B1 (rs7498665), MTCH2 (rs10838738), CDKAL1 (rs7754840), and near MC4R (rs12970134) were not significantly associated with the concurrence of type 2 diabetes (all P > 0.05, Table 6).