Tgfb1 transcription was increased in TC‐treated mice early in infection, with elevated TGFβ1 production observed in TC‐treated mice was most evident in epithelial cells, predominantly in the distal nephron, earlier in infection (up to 7 dpi) and then in non‐epithelial (CD45−, E‐cadherin−) cell types later in infection (7–28 dpi). Here, TGFB1 is linked to infection.