Moreover, our results also confirmed that SIX‐1 could regulate the expression level of lncRNA ATB via TGF‐β1 and that lncRNA ATB is required for SIX‐1‐mediated miR‐200s expression, suggesting that SIX‐1/lncRNA ATB/miR‐200s axis is one of the possible mechanisms that control BC metastases. Here, TGFB1 is linked to breast cancer.