To further draw attention to whether increased expression of SIX‐1 affects survival probability of BC patient, we screened a public database (http://kmplot.com/analysis/index.php?p=service%26cancer=breast) and confirmed that the overall survival (OS), recurrence‐free survival (RFS) and distant metastasis‐free survival (DMFS) of BC patients were longer in the low‐SIX‐1‐expression group than in the high‐SIX‐1‐expression group (Figure 1C), suggesting that SIX‐1 plays a pivotal role in BC development. The gene discussed is SIX1; the disease is breast cancer.