By using EMT‐related PCR array assay in MCF‐7‐SIX‐1‐OE and MDA‐MB‐231‐SIX‐1‐KD cells, we further found and confirmed that besides TGF‐β1, ZEB1 are also responsible for SIX‐1‐induced EMT in BC metastases (Figure 3). Here, SIX1 is linked to breast cancer.