Two of these CDGs manifest as severe congenital neutropenia caused by defects in Jagunal homolog 1 (JAGN1) and glucose-6-phosphatase catalytic 3 (G6PC3), one is a leukocyte adhesion deficiency type II due to defects in solute carrier family 35 member C1 (SLC35C1), one is a glycogen storage disease type I with neutropenia or neutrophil dysfunction (or both) caused by defects inSLC37A4, and the others show various degrees of lymphocyte and immunoglobulin impairment118,120–125. Here, SLC35C1 is linked to leukocyte adhesion deficiency type II.