Two of these CDGs manifest as severe congenital neutropenia caused by defects in Jagunal homolog 1 (JAGN1) and glucose-6-phosphatase catalytic 3 (G6PC3), one is a leukocyte adhesion deficiency type II due to defects in solute carrier family 35 member C1 (SLC35C1), one is a glycogen storage disease type I with neutropenia or neutrophil dysfunction (or both) caused by defects inSLC37A4, and the others show various degrees of lymphocyte and immunoglobulin impairment118,120–125. The gene discussed is SLC35C1; the disease is leukocyte adhesion deficiency.