NFE2L2 and hepatocellular carcinoma: Although only 60 genes showed overlap between Nrf2 and HIF1α in ChIP-seq (Fig. 6A), WikiPathway analysis (https://biit.cs.ut.ee/gprofiler/gost) revealed that both Nrf2 and HIF1α are the key regulators for the genes in metabolic and hepatocellular carcinoma (HCC) pathways (Fig. 6B).