Univariate and multivariate Cox regression analysis demonstrated that CD47 or ENO1 was an independent predictor for overall and disease-free survival of CRC patients (Figure S8F-G and Table 2-3), but receiver operating characteristic (ROC) curve and area under curve (AUC) values showed that the combination of CD47 and ENO1 have a better predictive performance than CD47 or ENO1 alone (Figure 7K-L). The gene discussed is ENO1; the disease is colorectal carcinoma.