NBN's overexpression is highly driven by its CNAmp in both primary tumors (TCGA database, P = 2.50×10-60) and cancer cell lines (GDSC database, P = 3.94×10-5), which was also observed in two independent serous ovarian carcinoma studies (Etemadmoghadam D, et al.38, 39, P = 2.45×10-7; Ducie J, et al.40, P < 10-5) (Figure S3C). The gene discussed is NBN; the disease is cancer.