AFP and neoplasm: We selected more impressive factors to perform multivariate Cox regression analysis, including pre-LT serum AFP level (>400ng/ml), histologic grade (poorly differentiated), TNM stage (stages 3-4), tumor size (≥5cm), number of nodules (≥3), Milan criteria (beyond), microvascular invasion and donor rs1927914 AG/GG genotype, and once again excluded tumor size and the number of nodules to prevent collinearity, as mentioned above.