For examples, lncRNA small nucleolar RNA host gene 20 (lncSNHG20) is upregulated and can promote cell proliferation and migration in non-small cell lung cancer 11, lncRNA Growth Arrest Specific 5 (lncGAS5) differentially regulates cell cycle arrest and apoptosis in human neuroblastoma through activating breast cancer type 1 susceptibility protein (BRCA1) and p53 12, H19 can promote tumor growth and indicate a poor prognosis in colorectal cancer 13. This evidence concerns the gene BRCA1 and colorectal cancer.