In the univariate Cox regression analysis (Table 3), tumor stage and patient age were significant prognostic factors (p<0.0001), and the methylation level of CHODL was also associated with an increased risk of cancer-related death (relative risk [RR], 0.467; 95% confidence interval [CI], 0.269-0.809; p<0.05). Here, CHODL is linked to cancer.