TWIST1 and nasopharyngeal carcinoma: In hematopietic stem cells, for example, TWIST1 binds to the promoter of Gata2 and induces its transcription (Kulkeaw et al., 2017), while in nasopharyngeal carcinoma cells, GATA2 induces EMT by binding to the promoter of Twist1 and activating its expression (Wang et al., 2017b).