Additionally, a study by Dong et al. reported that the levels of IL-8, TNF-α, IL-17, and IL-23 in the sputum and of IL-8 and IL-17 in the blood were markedly decreased after Lian Hua Qing Wen Capsule treatment in patients with acute exacerbation of chronic obstructive pulmonary disease 83. Here, IL17A is linked to chronic obstructive pulmonary disease.