Average lifetime daily consumption of more than 24.6 g ethanol was associated with around 30% increased CRC risk of the non-aberrant, more frequent subtypes (MSS, BRAF-wt, KRAS-wt, CIMP-low/neg) and not with the aberrant subtypes (MSI, BRAF-mut, CIMP-high), but no statistically significant differences were observed in heterogeneity testing between subtypes in this study. Here, KRAS is linked to colorectal carcinoma.