We noted that circulating CD117+ ILCs, in patients with LN (Fig. 1c), were significantly lower than that in HC; however, there was no difference in the percentage of IL-17-producing ILCs (which are conventionally regarded as IL-17A+ ILC3s) between HC and patients with renal disease, including LN (HC vs. LN, P = 0.1405). Here, IL17A is linked to lobular neoplasia.