Kallmann syndrome caused by ANOS1 gene mutations is inherited by X-linked recessive trait as it is located on chromosome X. FGFR1 and PROK2/PROKR2 lead to autosomal dominantly inherited type of CHH (Boehm et al. 2015; Maione et al. 2018). The gene discussed is PROKR2; the disease is cartilage-hair hypoplasia.