PPM1F and hepatocellular carcinoma: CircRNAs are much more stable as comparing to the linear RNAs transcripts and resistant to RNA enzyme decay, which makes circRNAs suitable for predictive marker.8, 9 For example, circRNA circSLC3A2 exhibits the oncogenic role in the HCC by sponging miR‐490‐3p/PPM1F axis.10 Circ‐10720 was positively promoted by the transcription factor Twist1 in HCC, which absorbs miRNAs that target vimentin, providing new insight for circular RNA‐based diagnostic and therapeutic strategies.11