CircRNAs are much more stable as comparing to the linear RNAs transcripts and resistant to RNA enzyme decay, which makes circRNAs suitable for predictive marker.8, 9 For example, circRNA circSLC3A2 exhibits the oncogenic role in the HCC by sponging miR‐490‐3p/PPM1F axis.10 Circ‐10720 was positively promoted by the transcription factor Twist1 in HCC, which absorbs miRNAs that target vimentin, providing new insight for circular RNA‐based diagnostic and therapeutic strategies.11 This evidence concerns the gene VIM and hepatocellular carcinoma.