IFNG and neoplasm: In summary, the gut microbiota may enhance the functions of DCs by increasing the potency of tumor antigen presentation and cytokine production, increase the formation of memory T cells and their trafficking from the mesenteric and draining lymph nodes to the TME, decrease Treg and MDSC numbers, and increase the recruitment and activation of IFN-γ-producing tumor antigen-specific effector T cells which together contribute to the modulation of the antitumor immune response.