In multivariate Cox proportional hazards analysis adjusted for age, sex, body mass index, estimated glomerular filtration rate, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, systolic blood pressure, smoking status, history of hypertension and diabetes mellitus, a high level of hsCK-MB was still an independent risk factor for all-cause mortality. The gene discussed is MB; the disease is hypertensive disorder.