Kleber et al. developed a new Vienna and Ludwigshafen CAD (VILCAD) biomarker risk score, which is a composite of age, haemoglobin A1c, LVEF, heart rate, NT-proBNP, sex, renin, 25-OH vitamin D, and cystatin C to predict the future long-term prognosis of patients with SCHD27. The gene discussed is NPPB; the disease is coronary artery disorder.