As presented in Figure 11A–11E and Figure 12A–12I, hsa_circ_0001955, hsa-miR-135b-5p, CDK4, MMP12 and RAB3IP were significantly upregulated whereas hsa_circ_0000977, hsa-miR-145-5p, FOXO1, MBNL1, MEF2C, RECK, PPM1E, TTLL7 and PCP4L1 were markedly downregulated in CRC when compared with normal controls, which were in accordance with GEO and TCGA data. This evidence concerns the gene MBNL1 and colorectal carcinoma.