GPT and Sepsis: Additionally, the levels of hepatic-injury markers (ALT and AST activities) were significantly higher in the plasma of rats with CLP-induced sepsis as compared to that in control rats (60.2 ± 5.5 vs 16.3 ± 1.85, P < 0.001, and 100.4 ± 6.4 vs 15.8 ± 2.87, P < 0.001, respectively; Figure 2D and 2E).