Numerous lines of evidence from cell lines and genetically engineered mice implicate CHD1 as a tumor suppressor, including in primary prostate cancer (Augello et al., 2019, Huang et al., 2011, Liu et al., 2012, Rodrigues et al., 2015, Shenoy et al., 2017, Zhao et al., 2017). The gene discussed is CHD1; the disease is prostate carcinoma.