Previous studies have shown that miRNAs play a key role in glioma, such as miR‐30a decrease tumorigenicity of glioma stem cells by targeting NT5E‐dependent AKT pathway18; miR‐1254 inhibits glioma progression by targeting CSF‐119; and miR‐769‐3p inhibits glioma tumour progression by suppressing ZEB2 and regulating Wnt signalling pathway.20 Here, NT5E is linked to central nervous system cancer.