MAPT and frontotemporal dementia: While bvFTD and bvFTD* cases were not distinct from each other (p = 0.2460), these analyses of protease-sensitive conformers indicate at least two strains of tau strains in FTD-MAPT P301L brains (noting that all three phenotypic variants of FTD showed similar profiles after PK treatment; Fig. 2e).